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The global population of individuals with gout increased in the past 30 years from 22 million to 53 million¹.

The sex ratio stayed consistent at 3:1 (male to female), but the gout incidence kept increasing over time¹.

Gout is a type of arthritis that arises due to the accumulation of uric acid crystals in the joints, causing intense discomfort, inflammation, and swelling. Purines, which are present in various foods and produced naturally by the body, give rise to uric acid. If the level of uric acid in the bloodstream exceeds the normal level, it can cause the formation of crystals that can accumulate in the joints, ultimately leading to the development of gout.

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One-third of patients with an acute gout flare have normal uric acid levels²
A high uric acid level increases the probability of gouty arthritis, but does not confirm the diagnosis²
Changes to diet and lifestyle can reduce uric acid levels by up to 18%³
Several studies have shown that less than 50% of gout patients surveyed were informed of the association between particular foods and gout²
Gout patients are at higher risk of coronary disease⁴
Patients with uncontrolled gout have a higher association with diabetes mellitus, CKD and congestive heart failure compared with well-controlled gout
Recent meta-analysis made in 2021 of four cohort studies with a mean follow-up of 11.2 years, showed that higher SU levels at baseline were associated with an increased risk of developing gout (dose-dependent) compared with baseline SU⁵

CKD = Chronic kidney disease

SU = Serum urate

Global, Regional, and National Prevalence of Gout From 1990 to 2019: Age-Period-Cohort Analysis With Future Burden Prediction. JMIR Public Health Surveill. 2023; 9: e45943. Published online 2023 Jun 7. doi: 10.2196/45943

Treatment Options for Gout. Bettina Engel, Johannes Just, Markus Bleckwenn, Klaus Weckbecker. Deutsches Ärzteblatt International | Dtsch Arztebl Int 2017; 114: 215-22

Khanna D, Fitzgerald JD, Khanna PP, et al. 2012 American College of Rheumatology guidelines for management of gout Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res. 2012;64:1431-1446.

The incidence and prevalence of cardiovascular diseases in gout: a systematic review and meta-analysis. Peter Cox1 · Sonal Gupta2 · Sizheng Steven Zhao3 · David M. Hughes4 Rheumatology International (2021) 41:1209-1219

Clinical practice guidelines management of gout 2021 (Second edition). Malaysian Health Technology Assessment Section (MaHTAS) Medical Development Division, Ministry of Health Malaysia

Gout relief:

It’s possible.

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